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Safety Equipment: Biological Ssafety Cabinets (BSCs)

Class I Biological Safety Cabinet

This is a ventilated cabinet for personnel protection with an unrecirculated inward airflow away from the operator. The air from the cabinet is exhausted through a HEPA filter: (a) into the laboratory and then to the outside of the building exhaust; (b) to the outside through the building exhaust; or (c) directly to the outside. The HEPA filter may be located in the exhaust plenum of the BSC or in the building exhaust. Some Class I BSCs are equipped with an integral exhaust fan, whereas others rely on the exhaust fan in the building exhaust system.

The Class I BSC was the first recognized BSC and, because of its simple design, is still in wide use throughout the world. It has the advantage of providing personnel and environmental protection and can also be used for work with radionuclides and volatile toxic chemicals. Because unsterilized room air is drawn over the work surface through the front opening, it does not provide product protection.

Safety Equipment: Biological Safety Cabinets: Class II Biological Safety Cabinet

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