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THE ORCBS > Biological Safety > Programs & Guidelines > Biosafety Manual >
Selection of a biological safety cabinet A BSC should be selected primarily in accordance with the type of protection needed: product protection; personnel protection against Risk Group 1-4 microorganisms; personnel protection against exposure to radionuclides and volatile toxic chemicals; or a combination of these. Table 3 shows which BSCs are recommended for each type of protection. Volatile or toxic chemicals should not be used in BSCs that recirculate exhaust air to the room, i.e. Class I BSCs that are not ducted to building exhaust systems, or Class IIA1 or Class IIA2 cabinets. Class IIB1 BSCs are acceptable for work with minute amounts of volatile chemicals and radionuclides. A Class IIB2 BSC, also called a total exhaust cabinet, is necessary when significant amounts of radionuclides and volatile chemicals are expected to be used.
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Safety Equipment: Biological Ssafety Cabinets (BSCs)
