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THE ORCBS > Biological Safety > Programs & Guidelines > Biosafety Manual >
Research-related activities involving prions or tissues containing prions have been on the rise at MSU in both the animal health and human health arenas. Because the infectious nature of prions is not well characterized and destruction of these particles goes beyond the techniques typically required for biohazard inactivation, work with these agents requires special considerations for biocontainment to minimize both occupational and environmental exposure risk. At this time, work with prion-risk materials at MSU is limited to research and diagnostic laboratory applications. A guidance document has been prepared that applies to these procedures only (See Appendix I ). Guidelines for use of prion-risk materials in conjunction with live animals will be developed if needed. Therefore, if future project plans call for use of live animals and prion-risk materials, please notify the MSU Biosafety Officer at the proposal-writing stage to perform a risk assessment and identify containment requirements. |
Guidelines for Prion Use 
