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THE
ORCBS > Radiation
Safety
> Radiation
Safety Manual
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 Bioassays
Conditions of the
broad license issued by the Nuclear Regulatory Commission (NRC) mandates
that bioassays are required for workers using certain types and amounts
of radioisotopes.
Individuals
performing or observing iodinations where one millicurie or more
of 125I is used are required to obtain a thyroid scan
after the iodination or use of the sodium iodide or potassium iodide
stock solution. A baseline thyroid scan should be conducted on workers
who have not previously used these kinds of 125I at Michigan
State University. Individuals must receive a thyroid scan bioassay
with the ORCBS at least 24 hours after each iodination or use of
free radioiodine, but not more than one week afterwards.
Also, individuals
handling greater than or equal to100 mCi of tritium (3H)
must submit a urine sample to the ORCBS for bioassay within 24 hours
of the handling. This bioassay must be performed each time this
amount of tritium is handled. Contact the ORCBS for further details
prior to urine bioassays.
If there appears
to be a likelihood that a significant internal exposure has occurred,
the Radiation Safety Officer may require further bioassays as deemed
necessary.
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