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Laboratory Design and Equipment

Working with radioactive materials requires the use of specially designed laboratories and equipment, and may not be conducted in offices or other unapproved locations. In fact, rooms to be used for such work must be examined and approved for the use of the types and quantities of radioactive materials to be used. This is part of the approval process. Most laboratories at Michigan State University meet the requirements for use of radiation.

Smooth, contiguous, non-absorbent surfaces such as stainless steel or linoleum are preferred in a radiation work area. A properly working chemical fume hood with flow rates of at least 100 feet per minute is required if fume hoods will be used for containing radioactive materials. Special filters and/or design is not generally necessary, but may be prudent in special cases. The rooms used must be capable of security, or in other words must be able to be locked to maintain the security requirements for radioactive materials.

In areas where contamination is likely, surfaces should be covered with absorbent and disposable material, such as poly-backed absorbent lab paper. (The paper should have the plastic side down, absorbent side up.) If you are in the process of designing a radioisotope lab, consult the Health Physics staff for information regarding design and vendor catalogues. Work areas should be localized to minimize the possibility of contamination spread, and also because surveys must be conducted for all areas where radioactive materials are used, stored or disposed.

Equipment such as glassware, tools, syringes, etc. used in the handling of radioactive materials should not be used for other work or allowed to leave the lab unless it can be shown that the equipment is free from removable contamination. It is strongly recommended that a designated and labeled storage area be used to store this equipment. Fume hoods with flow rates of at least 100 linear feet per minute should be used whenever working with radioactive materials where the potential for vaporization/volatilization exists (as is the case during iodination), or in handling stock solutions of radiotracers, because of the high activity concentration.

Clean Laboratory Conditions and Containment

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